Olanzapine Properties, Molecular Formula, Applications - WorldOfChemicals

Olanzapine Properties

Olanzapine

Molecule Structure Image

Description

 

Olanzapine is an atypical antipsychotic.Olanzapine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors. Olanzapine's antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors.Symptoms of an overdose include tachycardia, agitation, dysarthria, decreased consciousness and coma. Death has been reported after an acute overdose of 0.45g, but also survival after an acute overdose of 1500g

Chemical Properties

Appearance 476.035°C
Boiling Point 476.035 °C
Brand Name Olansek
Symbyax
Zydis
Zyprexa(Australia);(Belgium);(Canada Ontario);(Canada Quebec);(Denmark);(Japan);(New Zealand);(Norway\t)
Zyprexa Intramuscular
Zyprexa Zydis
CAS Number 132539-06-1
Density 1.324 g/cm3
IUPAC Name 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
InChI 1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
InChIKey KVWDHTXUZHCGIO-UHFFFAOYSA-N
Melting Point 195 °C
Molar Mass 312.43 g/mol
Molecular Formula C17H20N4S
Synonyms 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine;Lanzac;Zyprexa;2-Methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene;Amulsin;Zolafren;Zalasta;2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin