OSU-03012 Properties, Molecular Formula, Applications - WorldOfChemicals

OSU-03012 Properties

OSU-03012

Molecule Structure Image

Description

 

OSU-03012 is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. It may also cause cell death through the induction of stress in the endoplasmic reticulum.

Chemical Properties

CAS Number 742112-33-0
IUPAC Name 2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide
InChI 1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
InChIKey YULUCECVQOCQFQ-UHFFFAOYSA-N
Molar Mass 460.15 g/mol
Molecular Formula C26H19F3N4O
Synonyms 3-[(Tert-Butyldimethylsilyl)Oxy]Cyclopentan-1-Ol;2-Amino-N-{4-[5-(Phenanthren-2-Yl)-3-(Trifluoromethyl)Pyrazol-1-Yl]Phenyl}Acetamide;2-Amino-N-{4-[5-(Phenanthren-2-Yl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Phenyl}Acetamide