Pamidronic acid Properties, Molecular Formula, Applications - WorldOfChemicals

Pamidronic acid Properties

Pamidronic acid

Molecule Structure Image

Description

 

Pamidronic acid is used to prevent osteoporosis. It is marketed by Novartis under the brand name Aredia. It is used to prevent bone loss, and in certain cancers with high propensity to bone, such as multiple myeloma. In multiple myeloma, it is usually administered as an intravenous infusion, lasting about 3 hours. The therapy is repeated monthly, and lasts for the life of the patient. Due to its ability to sequester calcium in bone, it is also used to treat high calcium levels. It is also used as an experimental treatment of the bone disorder known as Osteogenesis Imperfecta, or brittle bones.

Chemical Properties

Appearance white crystalline powder
Boiling Point 658.7 °C
CAS Number 40391-99-9
Density 2.00 g/cm3
EINECS Number 254-905-2
IUPAC Name (3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
InChI 1S/C3H11NO7P2/c4-2-1-3(5,12(6,7)8)13(9,10)11/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11)
InChIKey WRUUGTRCQOWXEG-UHFFFAOYSA-N
Melting Point <300oC
Molar Mass 235.07 g/mol
Molecular Formula C3H11NO7P2
Refractive 1.611 n/D
Solubility Soluble
Synonyms (3-Amino-1-Hydroxypropane-1,1-Diyl)Bis(Phosphonic Acid);3-Amino-1-Hydroxypropane-1,1-Diphosphonic Acid;Amidronic Acid;Gcp 23339a;Hydrogen (3-Ammonio-1-Hydroxy-1-Phosphonopropyl)Phosphonate;Pamidronic Acid
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