Phentermine Properties, Molecular Formula, Applications - WorldOfChemicals

Phentermine Properties


Molecule 3D Structure Image
Molecule Structure Image



Phentermine is a psychostimulant drug of the phenethylamine class, with pharmacology similar to amphetamine. It is used medically as an appetite suppressant. Phentermine is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes. It is a central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines. High levels of these catecholamines tend to suppress hunger signals and appetite. The drug seems to inhibit reuptake of noradrenaline, dopamine, and seratonin through inhibition or reversal of the reuptake transporters. It may also inhibit MAO enzymes leaving more neurotransmitter available at the synapse. Phentermine (through catecholamine elevation) may also indirectly affect leptin levels in the brain.

Chemical Properties

Appearance Colourless Oily Liquid
Boiling Point 206°C
Brand Name Adipex P; Adiphene ; Anoxine-AM; Ionamin; Duromine; Metermine; Mirapront; Obephen; Obermine; Obestin30; Phentremene; Phentrol; Phenterex; Phentromin; Pro-Fast SA; Qnexa; Redusa; Panbesy; Phentermine Trenker; Obenix; Oby-Trim; Teramine; Zantryl; Sinpet (MX);Supremin (PH); Umine (NZ); Weltmine (KP)
CAS Number 122-09-8
ChEBI 8080
Density 0.938 g/cm3
IUPAC Name 2-Methyl-1-phenylpropan-2-amine
InChI 1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3
Molar Mass 149.23 g/mol
Molecular Formula C10H15N
Solubility Insoluble
Synonyms Phenethylamine, α, α-Dimethyl- (8CI); 1,1-Dimethyl-2-phenylethylamine;1-Phenyl-2-Methyl-2-Propylamine; Duromine; Inoamin; Ionamin; Linyl; Lipopill;Lonamin; Mirapront; Normephentermine; Omnibex; Phentermine;Phenyl-Tert-Butylamine; Wilpo; α, α-Dimethyl-b-Phenylethylamine; α, α-Dimethylbenzeneethanamine; α, α-Dimethylphenethylamine; α-Benzylisopropylamine