Phenylephrine Properties, Molecular Formula, Applications - WorldOfChemicals

Phenylephrine Properties


Molecule 3D Structure Image
Molecule Structure Image



Phenylephrine is a sympathomimetic amine that acts predominantly on α-adrenergic receptors. Phenylephrine is now the most common over-the-counter (OTC) decongestant. It is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs. Parenteral administration of phenylephrine causes a rise in systolic and diastolic pressures, a slight decrease in cardiac output, and a considerable increase in peripheral resistance. Phenylephrine also causes pulmonary vessel constriction and subsequent increase in pulmonary arterial pressure.

Chemical Properties

Boiling Point 341.1 °C
Brand Name AK-Dilate; AK-Nefrin; Adrianol; Alcon Efrin; Alconefrin Nasal Drops12; Alconefrin Nasal Drops 25; Alconefrin Nasal Drops 50; Alconefrin Nasal Spray 25; Biomydrin; Dilatair; Dimetane; Dionephrine; Doktors; Duration; I-Phrine; Isophrim;Isophrin; Isopto Frin; M-Sympathol; M-Sympatol; M-Synephrine; Mesaton; Mesatone; Mesatonum; Metasympatol; Metsatonum; Mezaton; Minims Phenylephrine; Mydfrin; Neo-Synephrine; Neo-Synephrine Nasal Drops; Neo-Synephrine Nasal Jelly; Neo-Synephrine Nasal Spray;Neofrin; Neophryn; Neosynephrine; Nostril; Nostril Spray Pump; Nostril Spray Pump Mild; Ocu-Phrin Sterile Eye Drops; Ocugestrin; Phenoptic; Prefrin; Prefrin Liquifilm; Pyracort D; Relief Eye Drops for Red Eyes; Rhinall; Spersaphrine; Vicks Sinex; Visadron
CAS Number 59-42-7
ChEBI 8093
Density 1.159 g/cm3
EINECS Number 200-424-8
IUPAC Name 3-[(1R)-1-hydroxy-2-methylaminoethyl]phenol
InChI 1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1
Melting Point 171°C
Molar Mass 167.20 g/mol
Molecular Formula C9H13NO2