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Piperacillin Properties

Piperacillin

Argininosuccinate synthase-Product_Structure
Molecule Structure Image

Description

 

Piperacillin is an extended spectrum beta-lactam antibiotic of the ureidopenicillin class. It is normally used together with a beta-lactamase inhibitor such as tazobactam. The combination has activity against many Gram-positive and Gram-negative pathogens and anaerobes, including Pseudomonas aeruginosa. Its main uses are in intensive care medicine, some diabetes-related foot infections and empirical therapy in febrile neutropenia.

Chemical Properties

Appearance White crystalline powder
Brand Name Pipracil
CAS Number 61477-96-1
ChEBI 8232
Density 1.51 g/cm3
EINECS Number 262-811-8
IUPAC Name (2S,5R,6R)-6-{[(2R)-2-[(4-Ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChI 1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1
InChIKey IVBHGBMCVLDMKU-GXNBUGAJSA-N
Molar Mass 517.555 g/mol
Molecular Formula C23H27N5O7S
Synonyms 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-;Piperacillin