Quinapril Properties, Molecular Formula, Applications - WorldOfChemicals

Quinapril Properties

Quinapril

ANAFIX RED HE8B-Product_Structure
Molecule Structure Image

Description

 

Quinapril is used in the treatment of hypertension and congestive heart failure. Quinapril is actually a prodrug. It is converted to its active metabolite, quinaprilat, in the liver. Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor, angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms.Quinaprilat competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II.Overdose may lead to severe hypotension.

Chemical Properties

Brand Name Accupril
Accuprin
Accupro
Acequin
Acuitel
Korec
Quinazil
CAS Number 85441-61-8
Melting Point 120-130°C
Molar Mass 438.52 g/mol
Molecular Formula C25H30N2O5
Solubility 1 mg/l
Synonyms Quinapril Hcl;Quinapril Hydrochloride;Quinaprilum [Latin]