Remoxipride Properties, Molecular Formula, Applications - WorldOfChemicals

Remoxipride Properties

Remoxipride

Molecule Structure Image

Description

 

Remoxipride is an atypical antipsychotic which was previously used in Europe for the treatment of schizophrenia but was withdrawn due to toxicity concerns. It was initially launched by AstraZeneca in 1990 and suspension of its use began in 1993. It acts as a selective D2 and D3 receptor antagonist and also has high affinity for the sigma receptor, possibly playing a role in its atypical neuroleptic action.

Chemical Properties

CAS Number 80125-14-0
Density 1.292 g/cm3
IUPAC Name (S)-3-Bromo-N-[(1-ethylpyrrolidin-2-yl)methyl]-2,6-dimethoxy-benzamide
InChI 1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1
InChIKey GUJRSXAPGDDABA-NSHDSACASA-N
Molar Mass 371.27 g/mol
Molecular Formula C16H23BrN2O3
Synonyms Roxiam;Benzamide,3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxy-;(-)-Remoxipride;(S)-Remoxipride;Remoxipride