Repaglinide Properties, Molecular Formula, Applications - WorldOfChemicals

Repaglinide Properties


Molecule Structure Image



Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal.

Chemical Properties

Boiling Point 672.9 °C
Brand Name GlucoNorm;Prandin
CAS Number 135062-02-1
Density 1.137 g/cm3
IUPAC Name 2-Ethoxy-4-[2-({(1S)-3-Methyl-1-[2-(1-Piperidinyl)Phenyl]Butyl}Amino)-2-Oxoethyl]Benzoic Acid
InChI 1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
Melting Point 129-130.2 °C
Molar Mass 452.58 g/mol
Molecular Formula C27H36N2O4