Reserpine Properties, Molecular Formula, Applications - WorldOfChemicals

Reserpine Properties

Reserpine

4-t-Butyl Styrene-Product_Structure
Molecule Structure Image

Description

 

Reserpine is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms, although because of the development of better drugs for these purposes and because of its numerous side-effects, it is rarely used today. The antihypertensive actions of reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.

Chemical Properties

Appearance Off-white Crystalline Powder
Brand Name Serpalan;Apoplon;Serpasil;Serpivite;Hiserpia;Raunervil;Raupasil;Rausedil;Rausedyl
CAS Number 50-55-5
ChEBI 28487
Class NA
Density 1.32g/cm3
EINECS Number 200-047-9
IUPAC Name Methyl-11,17α-dimethoxy-18β-[(3,4,5-trimethoxybenzoyl) oxy]-3β,20α-yohimban-16β-carboxylate
InChI 1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChIKey QEVHRUUCFGRFIF-MDEJGZGSSA-N
Melting Point 262-270 °C
Molar Mass 608.68 g/mol
Molecular Formula C33H40N2O9
NFPA 704 H-2,F-1,R-0,C-NA
PG NA
RTECS Number ZG0350000
Synonyms Methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(3,4,5-trimethoxyphenyl)carbonyloxy]- 3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate;Yohimban-16-carboxylicacid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3b,16b,17a,18b,20a)-;Reserpine;3,4,5-Trimethoxybenzoyl methyl reserpate;(3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester;(−)-Reserpine