Rofecoxib Properties, Molecular Formula, Applications - WorldOfChemicals

Rofecoxib Properties


Molecule Structure Image



Rofecoxib is a nonsteroidal anti-inflammatory drug.It selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is important for the mediation of inflammation and pain.It is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.

Chemical Properties

Appearance Crystalline Solid
Boiling Point 559.1°C
Brand Name Vioxx
CAS Number 162011-90-7
ChEBI 8887
Density 1.283 g/cm3
IUPAC Name 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
InChI 1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
Melting Point 164-166°C
Molar Mass 314.357 g/mol
Molecular Formula C17H14O4S
Solubility 559.1°C uses cookies to ensure that we give you the best experience on our website. By using this site, you agree to our Privacy Policy and our Terms of Use. X