Somatostatin Properties, Molecular Formula, Applications - WorldOfChemicals

Somatostatin Properties

Somatostatin

Molecule Structure Image

Description

 

Somatostatin is a 14-amino acid peptide. Somatostatin is produced by neuroendocrine neurons of the periventricular nucleus of the hypothalamus. It is also produced by several other populations that project centrally, and somatostatin receptors are expressed at many different sites in the brain. It regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. It is an inhibitor of growth hormone release from the anterior pituitary and hence an antagonist of GRF. Somatostatin suppresses the release of a variety of other hormones involved in the regulation of important physiological functions of the gastrointestinal tract. Somatostatin also inhibits TSH production.

Chemical Properties

Boiling Point 1970.9°C
CAS Number 51110-01-1, 38916-34-6
ChEBI 567331
Density 1.43 g/cm3
EINECS Number 254-186-5
InChI 1/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)
InChIKey NHXLMOGPVYXJNR-UYURUMNQSA-N
Molar Mass 1637.87 g/mol
Molecular Formula C76H104N18O19S2
Solubility 1 mg/ml
Synonyms Growth Hormone-Inhibiting Hormone; Somatotropin Release-Inhibiting Factor
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