Thiamphenicol Properties, Molecular Formula, Applications - WorldOfChemicals

Thiamphenicol Properties

Thiamphenicol

Thiamphenicol Structure-Molecule 3D Struture
Molecule 3D Structure Image
Thiamphenicol Molecular Structure-Molecule Struture
Molecule Structure Image

Description

 

Thiamphenicol is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia. It is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.

Chemical Properties

Appearance Off-white solid
CAS Number 15318-45-3
ChEBI 32215
Density 1.491 g/cm3
EINECS Number 239-355-3
IUPAC Name 2,2-Dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide
InChI 1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
InChIKey OTVAEFIXJLOWRX-NXEZZACHSA-N
Melting Point 163-166 °C
Molar Mass 356.223 g/mol
Molecular Formula C12H15Cl2NO5S
RTECS Number AB6680000
Synonyms Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-;(Methylsulfonyl)chloramphenicol;D-Thiophenicol;D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol;Dextrosulphenidol;Thiophenicol;Thiamphenicol
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