Ticagrelor Properties, Molecular Formula, Applications - WorldOfChemicals

Ticagrelor Properties

Ticagrelor

Molecule Structure Image

Description

 

Ticagrelor is an oral antiplatelet treatment for acute coronary syndromes (ACS) in a new chemical class called cyclopentyltriazolopyrimidines (CPTPs). Ticagrelor works by preventing the formation of new blood clots and maintaining blood flow in the body to help reduce a patient's risk of another cardiovascular event (called atherothrombotic events) such as a heart attack or cardiovascular death. Ticagrelor is the first reversibly-binding oral adenosine diphosphate (ADP) receptor antagonist. Ticagrelor is extensively metabolized in humans with approximately 27% of the dose excreted as the parent compound.

Chemical Properties

Brand Name Brilinta;Brilique;Possia
CAS Number 274693-27-5
IUPAC Name (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophenyl)Cyclopropyl]Amino}-5-(Propylsulfanyl)-3H-[1,2,3]Triazolo[4,5-d]Pyrimidin-3-yl]-5-(2-Hydroxyethoxy)-1,2-Cyclopentanediol
InChI 1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1
InChIKey OEKWJQXRCDYSHL-FNOIDJSQSA-N
Molar Mass 522.567 g/mol
Molecular Formula C23H28F2N6O4S