Tigecycline Properties, Molecular Formula, Applications - WorldOfChemicals

Tigecycline Properties


Molecule Structure Image



Tigecycline is a glycylcycline antibiotic. Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is given intravenously and has activity against a variety of gram-positive and gram-negative bacterial pathogens, many of which are resistant to existing antibiotics.

Chemical Properties

Boiling Point 890.922 °C
Brand Name Tygacil
CAS Number 220620-09-7
ChEBI 149836
Density 1.455 g/cm3
InChI 1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
Molar Mass 585.65 g/mol
Molecular Formula C29H39N5O8