Tranexamic Acid Properties, Molecular Formula, Applications - WorldOfChemicals
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Tranexamic Acid Properties

Tranexamic Acid

Tranexamic Acid Molecular Structure-Molecule Struture
Molecule Structure Image

Description

 

Tranexamic acid is a synthetic derivative of the amino acid lysine. It is used to treat or prevent excessive blood loss during surgery and in various other medical conditions. It is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, by binding to specific sites of both plasminogen and plasmin, a molecule responsible for the degradation of fibrin. Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding. Tranexamic acid competitively inhibits activation of plasminogen (via binding to the kringle domain), thereby reducing conversion of plasminogen to plasmin. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.

Chemical Properties

Appearance White Crystalline Powder
Boiling Point 300.2°C
Brand Name Amcha; Amikapron; Amstat; Anvitoff; Carxamin; Cyclocapron; Cyklokapron; Emorhalt; Frenolyse; Mastop; Rikavarin; Rikavarin-S; Tamcha; Tranexan; Transamin; Trasamlon; Ugurol
CAS Number 1197-18-8
ChEBI 48669
Density 1.096 g/cm3
EINECS Number 214-818-2
IUPAC Name Trans-4-(Aminomethyl)Cyclohexanecarboxylic Acid
InChI 1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
InChIKey GYDJEQRTZSCIOI-LJGSYFOKSA-N
Melting Point 300 °C
Molar Mass 157.21 g/mol
Molecular Formula C8H15NO2
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