fondaparinux sodium usp 95% Supplier - Shenzhen BST Science & Technology Co., Ltd
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fondaparinux sodium usp 95%

Description :

Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor. Apart from the O-methyl group at the reducing end of the molecule, the identity and sequence of the five monomeric sugar units contained in fondaparinux is identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparinand heparin sulfate (HS). Within heparin and heparin sulfate this monomeric sequence is thought to form the high-affinity binding site for the anti-coagulant factor antithrombin III (ATIII). Binding of heparin/HS to ATIII has been shown to increase the anti-coagulant activity of antithrombin III 1000 fold. In contrast to heparin, fondaparinux does not inhibit thrombin.
Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.

Seller Info :

Shenzhen BST Science & Technology Co., Ltd

Product Details :

Brandbst
Cas Number 114870-03-0
Appearancesolid
Gradeusp
Purity95%

Categories :

Pharmaceutical raw materials
Cardiovascular agents
About Suppliers :
Shenzhen BST Science & Technology Co., Ltd
Shenzhen BST Science & Technology Co., Ltd., founded in 2007, is a manufacturer of personal care functional ingredients in China and has ten years experience in import and export. Shenzhen BST Science & Technology Co., Ltd. Manufactures and sources more than 10 categories of personal care ingred Read More..
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