Properties
Aminophylline (CAS Number:317-34-0) is a bronchodilator drug composed of theophylline and ethylenediamine in the ratio of 2:1. Ethylenediamine is normally found as a dihydrate, which improves solubility. The compound occurs in powder form, either as white or yellow granules. Its chemical formula is C16H24N10O4. The compound has a bitter taste and has slight ammonia like odor. It is insoluble in ether and alcohol.
Production
Aminophylline manufacturers manufacture the chemical by adding theophylline to a solution of diamine in anhydrous alcohol. The precipitate is later filtered, washed with alcohol and dried. This results in the production of aminophylline powder.
Applications
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Aminophylline suppliers sell the chemical as an intravenous drug for the treatment of lung diseases like asthma, emphysema and bronchitis.
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The medical industries buy aminophylline for use in nuclear cardiology testing to reverse adenosine, dipyridamole and regadenosonbased infusions.
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Aminophylline suppliers supply the chemical to topical cream manufacturers, where it finds body fat reducing and anaphylactic shock treatment applications.
Toxicity
Aminophylline suppliers should provide warnings about the product’s sideeffects, such as headache, skin rash, stomach pain, vomiting, stomach upset, diarrhea, insomnia, restlessness and irritability.Overdose of the drug could lead to poisoning accompanied with difficulty in breathing, irregular heart rate, seizures and unconsciousness. There is a possibility of formation of toxic gases during fire or heating. Industries that buy aminophylline must be of its toxicity.
Handling and Storage
Aminophylline manufacturers must provide adequate ventilation to avoid build up of mist or vapor. Personnel handling the compound must use apt personal protective equipment. Thorough washing must be done post handling. The industries that buy aminophylline, apart from aminophylline suppliers must implement apt waste disposal measures to prevent environmental releases or occupational exposure. Dust collectors or filtration systems must be provided by aminophylline manufacturers to check the process emissions of this compound.
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