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Bortezomib (originally PS-341 and marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome inhibitor to be tested in humans. Cardiovascular safety pharmacology studies in monkeys show that lethal IV doses are associated with decreases in blood pressure, increases in heart rate, increases in contractility, and ultimately terminal hypotension. In monkeys, doses of 3.0 mg/m2 and greater (approximately twice the recommended clinical dose) resulted in progressive hypotension starting at 1 hour and progressing to death by 12 to 14 hours following drug administration.

Suzhou 2152Technology Co.,Ltd

No.32 Huoju Road ,National New&Hi-tech industrial development zone, suzhou, china

china china

bortezomib-Manufacturer

Bortezomib belongs to anti-cancer drug and the first therapeutic proteasome inhibitor drug. This anti-cancer drug is marketed with the brand name Velcade.Bortezomib. The mechanism of action in cancer patients involves by interrupting proteasomes activity. Bortezomib has side effects that found in cancer patients which are nausea, vomiting, diarrhea, constipation, and poor appetite.

CAS Number: 179324-69-7
Appearance: yellow solid

SPR ONCOCARE PVT LTD

12, ring road 100 ft bsk 3rd stage , bangalore, bangalore, india

india india

Bortezomib-Trader
cas 179324-69-7

MC Chemicals Co., Ltd

No.787 KangQiao Road, shanghai, china

china china

bortezomib-Manufacturer bortezomib-Trader

ChemBo Pharma Co., Ltd.

Unit A, 9/F Silvercorp, International Tower, 707-713 Nathan Road, Mongkok, Kowloon, Hong Kong, hong kong

hong kong hong kong

bortezomib-Trader

Sai Teja Drugs and Intermediates Pvt Ltd

Sy. No.543/A, 544/A, Seeta Vani Gudem, Boodhan Pochampally,, india

india india

bortezomib-Manufacturer

Mascot IE Co., Ltd

B802, Xingbei Development Building, Xinbei District,, china

china china

bortezomib-Manufacturer bortezomib-Trader

VAV Life Sciences Pvt. Ltd.

51/B Mittal Court,224 Nariman Point Mumbai,India, india

india india

bortezomib-Manufacturer

Syntide Medi-Chem Technology (China)Limited

No. 5 Shangdi Kaituo Road,Zhongguancun Biomedical Garden, hong kong

hong kong hong kong

bortezomib-Trader

Reco Tech Limited

No.6, Laizhen, Xiaoyingdong Road, Xiaoyingqiao East, Haidian District, Beijing, china

china china

bortezomib-Trader

Shanghai Forxine Pharmaceutical Co. Ltd.

237 Xitai Road, Xuhui Functional Material Park, Shanghai, China, china

china china

bortezomib-Manufacturer

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