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ephedrine industrial grade 99.34%

ephedrine

industrial grade
99.34%

Ephedrine is a medication and stimulant. It is often used to prevent low blood pressure during spinal anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment. It is of unclear benefit in nasal congestion

CAS Number: 134-72-5
Appearance: 0000

What is Ephedrine?

Ephedrine (CAS No: 299-42-3) is an alkaloid, a medication and a stimulant. Ephedrine is a hydroxylated combination of phenethylamine and sympathomimetic amine. Ephedrine molecular formula is C10H15NO, it has a boiling point of 255 degree Celsius and melting point 37-39 degree Celsius. Ephedrine is also called as 2-(Methylamino)-1-Phenylpropan-1-Ol, Bronkaid, (-)-ephedrine, Fedrin, (1R,2S)-(-)-Ephedrine.

Ephedrine was isolated first in 1885 then came in 1926 for the commercial purpose. Ephedrine is there in WHOs list of essential medicines as most effective and safe medicine required in the health industry.

 

Applications of Ephedrine

- Ephedrine is used for the treatment of disorders like asthma, heart failure, CNS and urinary incontinence.

- It is used in spinal anaesthesia during delivery, for preventing hypotension, treatment of nasal congestion, rhinitis, sinusitis.

- Ephedrine acts as bronchodilators and increases blood pressure.

- Ephedrine can be used for short term weight loss, mainly fat loss, and decreases gastric emptying.

- As ephedrine have a structural similarity of methamphetamine, it is suitable to be used for creating methamphetamine through chemical reduction.

- It is used in bulk quantity as chiral auxiliary for chemical synthesis.

 

Sources of Ephedrine

Agricultural:

Ephedrine is extracted from the plant Ephedra sinica and other genus ephedra members. China is the largest supplier of ephedrine raw materials.

Synthetic:

I-ephedrine manufactured today is made synthetically by extraction and isolation process of E.sinica is no more cost effective.

Biosynthetic:

Ephedrine was thought to be produced by amino acid L- phenylalanine modification, this way is now disproven. New pathway suggests that phenylalanine forms cinnamoyl-CoA by the enzymes phenylalanine ammonia-lyase and acyl CoA ligase, then it goes under reaction with a hydratase attaching alcohol functional group. Then, it is reacted with retroaldolase, producing benzaldehyde, which later reacts with pyruvic acid to join a two-carbon unit. Later the product goes through transamination and methylation to form ephedrine.

 

Ephedrine Warnings/ Hazards

Continual use can result in anxiety, fear, restlessness. High blood pressure, glaucoma, pheochromocytoma and thyrotoxicosis. Ephedrine can cause headache, respiratory problem, fever, pallor, nose and throat dryness, precordial pain, sweating, mild epigastric distress, anorexia or nausea. It is harmful if swallowed. It is toxic by ingestion.

 

Handling, Storage and Sale

Ephedrine must be stored in light-resistant containers and it is highly hygroscopic so should be kept in cool and free from moisture place. Temperatures must not exceed 8EC in ephedrine containers.

The sale of drugs containing ephedrine is restricted to licensed health care pharmacist, distributor, manufacturer or wholesaler or any of these persons agent. Ephedrine manufacturers, suppliers or wholesales is required to report to police in case of a suspicious order. You can buy ephedrine online through licensed ephedrine suppliers or manufacturers.

 

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