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Ethyl acetate (CAS Number: 141-78-6) is an organic compound with the chemical formula C4H8O2. The other names of the compound are acetic ether, acetic ester and ethyl ester of acetic acid. Ethyl acetate is a colorless liquid and has a distinctive sweet odor. It is soluble in water, acetone, benzene, ethanol and diethyl ether.



Ethyl acetate manufacturers industrially manufacture the chemical through Fischer esterification reaction of acetic acid and ethanol. This reaction is accelerated though acid catalysts and equilibrium is shifted to the right though water removal.

Ethyl acetate manufacturers also manufacture it through Tishchenko reaction through the combination of two equal portions of acetaldehyde with an alkoxide catalyst.

2 CH3CHO → C4H8O2

Ethyl acetate manufacturers also use silicotungstic acid to manufacture ethyl acetate through the alkylation of acetic acid with ethylene.

C2H4 + CH3CO2H →C4H8O2



  • Ethyl acetate suppliers supply the chemical mainly as a solvent and diluent, owing to its low toxicity, low cost and bearable odor.

  • Nail polish removal companies buy ethyl acetate for use in its production.

  • Coffee and tea industries buy ethyl acetate to decaffeinate coffee beans and tea leaves.

  • Ethyl acetate suppliers sell the chemical as an activator or hardener to paint manufacturers.

  • Ethyl acetate suppliers also supply the chemical for use in fruits, perfumes and confectionery.

  • It finds applications in laboratory for extractions and column chromatography.

  • Ethyl acetate finds entomological application as an asphyxiant in insect collection and study.



Exposure to ethyl acetate can lead to the irritation of the eyes, nose, and throat. Over exposure to ethyl acetate could cause drowsiness, weakness and unconsciousness. This chemical is an irritant to the mucous and conjunctiva membrane of the respiratory tract. At high concentrations, it can result in symptoms of central nervous system depression, temporary opacity of the cornea, pulmonary edema with hemorrhages, eruptions of the skin, liver damageand secondary anemia. Ethyl acetate manufacturers and ethyl acetate suppliers should be aware of the toxic effects of the chemical.


Handling and Storage

Ethyl acetate suppliers and industries that buy ethyl acetate must keep the container tightly closed away from sources of ignition, flames, sparks or heat. Adequate ventilation should be provided. It must be kept away from incompatible substances. The work area must be equipped with a safety shower and eye wash facility. Industries that buy ethyl acetate must carefully handle and store the chemical.


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