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Fondaparinux Sodium Suppliers

Hefei TNJ Chemical Industry Co., Ltd.

D1508, Xincheng Business Center, Qianshan Road,, china

china china

fondaparinux fondaparinux

Glixx Laboratories Inc

63 South Street, Suite 130, united states

united states united states

fondaparinux fondaparinux

Pharmaffiliates Analytics & Synthetics (P) Ltd

Verified Supplier

Plot Number 225 ,Industrial Area, Phase II, india

india india

fondaparinux

Carbosynth Limited

Axis House, High Street, Compton, united kingdom

united kingdom united kingdom

fondaparinux fondaparinux

FINETECH INDUSTRY LIMITED

Verified Supplier

NO. 456 CHUKANG ROAD,, china

china china

fondaparinux fondaparinux

Wuxi Mizat Chemical Technology Co., Ltd.

Wuxing Road 538#, Wuxi, Jiangsu, 214400, China, china

china china

fondaparinux fondaparinux

Archie Chem

54 St James Street,, united kingdom

united kingdom united kingdom

fondaparinux
fondaparinux sodium usp 95%

Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor. Apart from the O-methyl group at the reducing end of the molecule, the identity and sequence of the five monomeric sugar units contained in fondaparinux is identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparinand heparin sulfate (HS). Within heparin and heparin sulfate this monomeric sequence is thought to form the high-affinity binding site for the anti-coagulant factor antithrombin III (ATIII). Binding of heparin/HS to ATIII has been shown to increase the anti-coagulant activity of antithrombin III 1000 fold. In contrast to heparin, fondaparinux does not inhibit thrombin.
Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.

CAS Number: 114870-03-0
Appearance: solid

Shenzhen BST Science & Technology Co., Ltd

9/F Zhilianjia Building, Longxiang Road, shenzhen, china

china china

Fondaparinux

Wessex Fine Chemicals Ltd

Blackthorn House, Bridge Road,, united kingdom

united kingdom united kingdom

fondaparinux

Cayman Chemical Company

1180 East Ellsworth Road,, united states

united states united states

fondaparinux fondaparinux

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