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Fumaric Acid

Fumaric acid (CAS no: 110-17-8) with the chemical formula C4H4O4 also known as trans-butenedioic acid, is a colorless white crystalline chemical component extensively found in nature. Fumaric acid is a vital intermediate in the tricarboxylic acid cycle for organic acid biosynthesis in humans and other mammals. Fumaric acid is also an essential ingredient in plant life.



Fumaric acid suppliers produce fumaric acid by the isomerization of maleic acid, which is produced from maleic anhydride. Maleic anhydride is then industrially produced by catalytic oxidation of right hydrocarbons in the gas phase. Benzene is utilized to be the predominant starting material, but oxidation of n-butane or n-butane–n-butene combination has become more important.

The butane oxidation reaction equation to maleic anhydride is: C4H10 + 3.5O2 → C4H2O3 + 4H2O.



- Industries buy fumaric acid as a raw material in the polymers and the increase of cost of petroleum-based fumaric acid raise interest in fermentation processes for production of this compound from renewable resources.

- It is used as the first medicine to treat psoriasis, a skin condition

- Fumaric Acid is used as acidity regulator in beverage, such as in protein beverages, and fruit juice drinks.

- Pharmaceuticals industries buy and use fumaric acid for treatment of Psoriasis. Fumaric acid, in its chemical structure form is known as fumaric acid esters, have shown to be effective against psoriasis symptoms. Fumaric acid manufacturers use for manufacturing of Psoriasis medicines.

- Health and personal care industries buy to Fumaric acid to use as PH adjuster which is used in cosmetics for instance for using in bath products, hair and skin care products, and makeup.

- In agricultural industries buy and use Fumaric acid as in piglet feed at the time of post-weaning period. Fumaric acid can alter pH value reveal improved weight gain, food consumption and feed conversion ratio.

- It is used as an acidulent, curing accelerant and a flavoring agent in wheat and corn tortillas.

- Fumaric acid can also be employed as a substitute for tartaric acid and at certain times in place of citric acid.

- Fumaric acid is made use in the manufacturing of polyester resins and polyhydric alcohols and also as a mordant for dyes.



When inhaled of dust of fumaric acid it may cause respiratory irritation. Compound is non-toxic when ingested. A long lasting contact with eyes or skin may cause irritation.


Storage and Handling

Fumaric acid is stable when it is subject to degradation by both aerobic and anaerobic microorganisms. After heating in sealed vessels with water at 150–170°C it changes into DL-malic acid. Fumaric acid suppliers and manufacturers must store the bulk material in a well-closed container in a cool, dry place.


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