Isophorone
Isophorone is an α, β-unsaturated cyclic ketone. It is a colourless liquid with a characteristic peppermint-like odor, although commercial samples can appear yellowish. The chemical formula of isophorone is C9H14O and the molar mass is 138.210 g·mol−1. Isophorone is used as a solvent and as a precursor to polymers, it is produced on a large scale industrially.
Isophorone Production
The isophorone manufacturer uses the following method of producing isophorone commercially is to feed acetone and an aqueous solution of an alkali catalyst to the upper section of a pressure distillation reactor which contains a refluxing mixture of acetone/water azeotrope (80:20% w/w respectively) and alkali catalyst (<0.1% w/w) at a temperature in the range 150° to 300° C, usually 200° to 240° C and a pressure in the range 30-35 bar. The lower part of the pressure still operates as a stripping section, from where unconverted acetone passes as an overhead azeotrope product with water and is condensed at the top of the column to produce the reflux. The isophorone produced by this process tends to be contaminated to an undesirable degree with colour-formers which are virtually inseparable from isophorone by simple distillation.
Physical Properties
The Isophorone is a water-white colored liquid with a peppermint-like odor The chemical formula for isophorone is C 9 H 14 O and the molecular weight is 138.21 g/mol.The vapor pressure for isophorone is 0.3 mm Hg at 20 °C and it has an octanol/water partition coefficient (log K ow ) Isophorone has an odor threshold of 0.20 parts per million (ppm). Isophorone is slightly soluble in water.
Isophorone Uses:
The isophorone manufacturers will develop the isophorone where it can be used commercially by keeping in mind all the physical and chemical properties before distributing it to the isophorone sellers.
- Isophorone is used mainly as a solvent for concentrated vinyl chloride/acetate-based coating systems for metal cans, other metal paints, nitrocellulose finishes, and printing inks for plastics.
- Isophorone is also used in some herbicide and pesticide formulations and in adhesives for plastics, polyvinylchloride, and polystyrene materials.
- Isophorone is an intermediate in the synthesis of 3,5-xylenol, 3,3,5-trimethylcyclohexanol, and plant growth retardants.
Health Hazard Information / Acute Effects:
People dealing with isophorone like manufacturers, isophorone supplier or who buy isophorone are effected by the following symptoms:
- The only acute effects of isophorone reported in humans are irritation of the skin, eyes, nose, and throat, headache, and dizziness.
- Exposure to a high concentration of isophorone via inhalation in animals causes inactivity and coma. Tests involving acute exposure of rats and guinea pigs have shown isophorone to have moderate toxicity from oral and inhalation exposure.
- Chronic Effects (Noncancer): Dizziness, fatigue, and depression have been experienced by workers exposed to isophorone over a long term period. Animal studies indicate that long-term inhalation of high concentrations of isophorone causes central nervous system effects such as narcosis, staggering, depression, ataxia, lethargy, prostration, and coma.
First Aid Measures
People dealing with isophorone like manufacturers, isophorone supplier or who buy isophorone must be aware of following safety measures:
- Wash affected area with soap and plenty of water. Remove contaminated clothing
- Get medical attention if symptoms occur. Wash clothing before reuse. Destroy contaminated leather items such as shoes, belts, and watchbands.
- Immediately flush eyes with water; remove contact lenses, if present, after the first 5 minutes, then continue flushing eyes for at least 15 minutes.
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