Properties
Kaempferol (CAS Number:520-18-3) is a flavanol, which is a type of flavonoid, present in plants. It is a yellow crystalline solid that is soluble in ether, ethanol and water. The chemical formula of the compound is C15H10O6. IUPAC name of the flavanol is 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one. Kaempferol suppliers supply the chemical by other names like kaempherol, robigenin, pelargidenolon,rhamnolutein,rhamnolutin,populnetin,trifolitin,kempferol and swartziol.
Production
Kaempferol manufacturers biosynthesize kaempferol through the conversion of phenylalanine into 4-coumaroyl-CoA, which combines with 3 malonyl-coA molecules. This leads to the production of tetrahydroxychalcone by action of enzyme chalcone synthase. This is followed by the conversion of naringenin chalcone is to naringenin, which is then converted to hydroxyl group. Kaempferol manufacturers then add this hydroxyl group to produce dihydrokaempferol, in which a double bond is introduced to produce kaempferol.
Applications
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Drug manufacturers buy kaempferol, owing to its pharmacological activities like anti-inflammatory, antioxidative, antimicrobial, neuroprotective, anticancer, antitumor, anti-osteoporotic, antidiabetic, analgesic, anxiolytic, antiestrogenic and antiallergic activities.
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Kaempferol suppliers supply the chemical for the manufacture of atherosclerosis prevention medicines. Kaempferol is used as human metabolites.
Hazards
Dermal exposure can lead to irritation and corrosion of skin. It can cause serious eye irritation. If the flavonoid is ingested, it can lead to the irritation of the respiratory tract and organ toxicity. Kaempferol can cause genetic defects. Kaempferol manufacturers, kaempferol suppliers and industries that buy kaempferol must be aware of its hazards.
Safety
Kaempferol suppliers must pack the chemical under an inert gas, owing to its toxicity.Container must be tightly kept closed by industries that buy kaempferol in their facilities. Local ventilation, process enclosures or other engineering controls must be provided by kaempferol manufacturers and kaempferol suppliers to control airborne particulates.Facilities must be equipped with an eyewash and a safety shower facility, where the chemical is stored or utilized. Personnel handling the compound must wear protective clothing.
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