Grape seed extract, B2G2, encouragescell death known as apoptosis in prostate cancer cells

Grape seed extract kills prostate cancer cells, finds new study

6:59 AM, 7th December 2013
Research on grape seed extract
Most active component of grape seed extract, B2G2, kills prostate cancer cells while leaving healthy cells unharmed.

WASHINGTON DC, US: A new study has revealed that the synthesis of the most active component of grape seed extract, B2G2, encourages the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed.

“We’ve shown similar anti-cancer activity in the past with grape seed extract, but now we know B2G2 is its most biologically active ingredient which can be synthesized in quantities that will allow us to study the detailed death mechanism in cancer cells,” said Alpna Tyagi, PhD, of the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences.

The effectiveness of grape seed extract has already been shown in previous studies, however, Tyagi said that until recently, they didn’t know which constituent of the grape seed extract created this effect. This naturally occurring compound, is a complex mixture of polyphenols and also so far it has been unclear about the biologically active constituents of grape seed extract against cancer cells.

According to Tyagi, B2G2 is the most active compound, but it is expensive and it takes a long time to isolate B2G2 from grape seed extract. The current study reported the success of this effort, including the ability to synthesize gram-quantity of B2G2 reasonably quickly and inexpensively.

© ANI News

0 Comments

Login

Your Comments (Up to 2000 characters)
Please respect our community and the integrity of its participants. WOC reserves the right to moderate and approve your comment.

Related News


Beer increases life span, while coffee shortens

TEL AVIV, ISRAEL: Researchers at Tel Aviv University have discovered that coffee can shorten life expectancy, while beer can increase it. Scientists h ...

Read more
Silkworms fed with dyed leaves spin coloured silk

WASHINGTON, US: Cultivated silkworms find use in fines clothing, are obtained by spinning luxurious white silk fibres. But current dyeing practices pr ...

Read more
Statoil appoints executive vice president for development and production, Nylund

STAVANGER, NORWAY: Arne Sigve Nylund has been appointed executive vice president for Development and Production of Statoil Norway. Nylund will assume ...

Read more
Shell exits GTL project in Louisiana, US

PARIS, FRANCE: Royal Dutch Shell plc will not move forward with the proposed 140,000 barrels per day Gulf Coast gas-to-liquids (GTL) project in Louisi ...

Read more
Amyris, Total JV for renewable diesel and jet fuel

PARIS, FRANCE: Amyris and Total have formed Total Amyris BioSolutions, a 50-50 joint venture that holds exclusive rights and a license under Amyris&rs ...

Read more
BASF to sell PVC modifier business to Kaneka

LUDWIGSHAFEN, GERMANY: BASF has signed a contract to sell its Vinuran PVC modifier business to Kaneka Belgium NV, a subsidiary of Kaneka Corporation, ...

Read more