Lonza, Avalanche joint venture gene therapy

Lonza, Avalanche joint venture for gene therapy

12:25 PM, 16th May 2012
Lonza, Avalanche joint venture for gene therapy

SAN FRANCISCO/HOUSTON, US: Avalanche Biotechnologies and Lonza announced a manufacturing collaboration focused on process development and scale-up efforts for the manufacturing of adeno-associated viral (AAV) vectors for gene therapy. AAV vectors are rapidly becoming one of the most promising gene delivery vehicles for the treatment of various diseases including inherited retinal disorders, age-related macular degeneration (AMD), hemophilia B, congestive heart failure, Parkinson’s disease and others. 

Avalanche and Lonza will make the technology available to third parties and share in the revenue. The Avalanche/Lonza manufacturing collaboration will focus on the development and high-yield production of AAV vectors based on a novel technology that uses stable baculovirus. This technology was licensed by Avalanche from Virovek, who will also play a key role in the collaboration. 

“We are delighted to have such a skilled and reputable manufacturing partner in Lonza to help us advance our robust research and development programmes using AAV to treat macular degeneration and other blinding diseases. By making our combined technology available to third parties, we hope to allow the entire AAV field to benefit from this best-in-class production process,” said Thomas W Chalberg, CEO, Avalanche Biotechnologies Inc.

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