Mistletoe may fight obesity-related liver disease

Mistletoe may fight obesity-related liver disease

12:20 PM, 24th December 2014
Mistletoe may fight obesity-related liver disease
Scientists are studying a substance in Korean mistletoe as a possible candidate for treating obesity-related liver disease.

WASHINGTON DC, US: Mistletoe may have better effect on liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice. Their study appears in ACS’ Journal of Agricultural and Food Chemistry.

Researcher Jungkee Kwon and colleagues noted that, according to recent research, Korean mistletoe produces a number of biologically active compounds. These include familiar ones such as steroids and flavonoids. Also, extracts from the plant have shown anti-obesity effects, but no one had confirmed which specific molecules were involved. Kwon’s team wanted to investigate the matter and see if the key ingredient could also help fight fatty liver disease, which is associated with obesity and can progress to liver failure in some cases.

The researchers identified viscothionin as the compound in Korean mistletoe that affects fat metabolism in the liver. When they treated obese mice with it, their body and liver weights dropped. The scientists concluded that viscothionin could be explored as a potential therapeutic agent for the treatment of nonalcoholic fatty liver disease.

 

© American Chemical Society News

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