2018 Nobel Prize in Chemistry awarded work proteins

Proteins research bags 2018 Nobel Prize in Chemistry

9:46 AM, 3rd October 2018
2018 Nobel Prize in Chemistry
Frances H. Arnold, George P. Smith and Gregory P. Winter wins 2018 Chemistry Nobel Prize.

STOCKHOLM, SWEDEN: The 2018 Nobel Prize in Chemistry is finally revealed. Researchers win the Nobel Prize for their work harnessing the power of evolution to develop proteins that solve humankind's chemical problems.

The Royal Swedish Academy of Sciences awarded the Prize with one half to Frances H. Arnold, at California Institute of Technology, Pasadena, US “for the directed evolution of enzymes,” and the other half jointly to George P. Smith at the University of Missouri, Columbia, US and Gregory P. Winter at the MRC Laboratory of Molecular Biology in Cambridge, UK “for the phage display of peptides and antibodies.

The Royal Swedish Academy of Sciences said that this year’s Chemistry Laureates have taken control of evolution and used the same principles – genetic change and selection – to develop proteins that solve humankind’s chemical problems.

The methods that the 2018 Nobel Prize laureates have developed are now being internationally developed to promote a greener chemicals industry, produce new materials, manufacture sustainable biofuels, mitigate disease and save lives, said the Academy.

Frances Arnold performed the first “directed evolution” of enzymes, which are proteins that catalyse chemical reactions. Enzymes produced through directed evolution are used to manufacture everything from biofuels to pharmaceuticals.

George Smith developed a method known as phage display, where a bacteriophage – a virus that infects bacteria – can be used to evolve new proteins.

Gregory Winter has used phage display to produce new pharmaceuticals. Today phage display has produced antibodies that can neutralise toxins, counteract autoimmune diseases and cure metastatic cancer.

The Nobel Prize in Chemistry for 2017 was jointly awarded to 3 scientists i.e. Jacques Dubochet, Joachim Frank and Richard Henderson for the development of cryo-electron microscopy, which both simplifies and improves the imaging of biomolecules.

What Nobel Prize basically mean?

Nobel Prize is an annual honour given every year for the most prominent work done in various fields like Chemistry, Physics, Economics, Medicine, Literature & prominently for promoting the peace. It is considered as one of the most powerful & prestigious honours in the world. The first Noble Prize was given in the year 1901, though the idea of honouring with the Nobel Prize was initiated by Alfred B. Nobel, a Swedish Chemist & the one who introduced Dynamite to the world. Nobel Prize is presented every year in Sweden & is the responsibility of Royal Swedish Academy of Sciences to handle or govern the award in Chemistry.

The first person to get Nobel Prize in Chemistry was Jacobus Henricus van 't Hoff of Netherlands for discovering the laws of Chemical Dynamics & Osmotic Pressure in solutions.

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